1614High Rates of Preterm Birth and Small for Gestational Age in a Cohort of HIV Infected Women in Canada: Role of Ritonavir Boosted Regimens?
نویسندگان
چکیده
Cohort of HIV Infected Women in Canada: Role of Ritonavir Boosted Regimens? Fatima Kakkar, MD, MPH; Isabelle Boucoiran, MD, MSc; Terry Lee, PhD; Joel Singer, PhD; Laura J. Sauve, MD, MPH; Lindy M. Samson, MD, MSc; Deborah Money, MD; Infectious Diseases, CHU Sainte-Justine, Université de Montréal, Montréal, QC, Canada; Obstetrics and Gynecology, British Columbia Women’s Hospital and Health Center, Vancouver, BC, Canada; CIHR Canadian HIV Trials Network, Vancouver, BC, Canada; School of Population and Public Health, Vancouver, BC, Canada; Infectious Diseases, British Columbia Women’s and Children’s Hospital, Vancouver, BC, Canada; Childrens Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada; British Columbia Women’s Hospital and Health Center, Vancouver, BC, Canada
منابع مشابه
Risk factors for pre-term birth in a Canadian cohort of HIV-positive women: role of ritonavir boosting?
BACKGROUND The risk of pre-term birth (PTB) associated with the use of protease inhibitors (PIs) during pregnancy remains a subject of debate. Recent data suggest that ritonavir boosting of PIs may play a specific role in the initiation of PTB, through an effect on the maternal-fetal adrenal axis. The primary objective of this study is to compare the risk of PTB among women treated with boosted...
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BACKGROUND In Canada, the majority of HIV-positive pregnant women receive combination antiretroviral therapy that includes a ritonavir-boosted protease inhibitor to prevent mother-to-child HIV transmission. However, protease inhibitor-based combination antiretroviral therapy has been associated with increased rates of preterm, low birth weight, and small for gestational age births. Our previous...
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BACKGROUND The association between combination antiretroviral (cARV) therapy use by human immunodeficiency virus (HIV)-infected women during pregnancy and risk of prematurity is still controversial. We explored this question, focusing on the initiation of ritonavir-boosted protease inhibitors (PIs) during pregnancy, which is now standard care. METHODS Trends in prematurity (<37 gestational we...
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BACKGROUND Angiogenic processes in the placenta are critical regulators of fetal growth and impact birth outcomes, but there are limited data documenting these processes in HIV-infected women or women from low-resource settings. OBJECTIVE We sought to determine whether angiogenic factors are associated with adverse birth outcomes in HIV-infected pregnant women started on antiretroviral therap...
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Background & Aim: It is important to identify modifiable causes of preterm delivery and low birth weight which are strong predictors of infants;apos later health status and survival. Research findings show that there are less low birth weight and preterm labors in the communities that have high intake of sea food. Consumption of Sea foods rich in w3 fatty acid can increase birth weight by prolo...
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